HIV/AIDS Treatment Research
The Thai Red Cross AIDS Research Centre’s HIV-NAT and SEARCH sub-units initiate and conduct research that is relevant to Thailand and the region. We contribute to the global efforts in treating and preventing HIV.
is the largest international HIV clinical research units within the TRC-ARC. It was established in 1996 as a collaboration between the TRC-ARC, the Kirby Institute of Infections and Immunity in Society/University of New South Wales in Sydney, Australia and the Amsterdam institute in Global Health and Development in Amsterdam, The Netherlands. HIV-NAT has been in the forefront in the field of HIV clinical research in Thailand and in the SEA region. It has initiated and led multi-site and multi-national studies on a broad area of HIV clinical trials from pharmacokinetics and efficacy of ART to hepatitis B (HBV) and C (HCV), tuberculosis (TB), human papilloma viral (HPV) co-infections and HIV- and ART-related comorbidities to responses to immunizations. HIV-NAT has proven track record of fast enrollment and efficient conduct of complex trials.
HIV-NAT has conducted over 200 studies and 350 publications to date (as of December 2012). HIV-NAT is the country coordinator for NIAID trials as part of the INSIGHT and CIPRA networks (included 2 sites in Cambodia), and is the regional coordinating center for pediatric HIV studies in 4 countries in SEA under the TREAT Asia Network, a branch of the Foundation for AIDS Research (amfAR).
The research at HIV-NAT has led to implementation at the national level. HIV-NAT works closely with the Ministry of Public Health in planning and leading clinical trials that are relevant to government policy.
is a collaboration between the TRC-ARC, the University of Hawaii and the US Military HIV research program (USMHRP) to conduct studies on acute HIV infection/HIV cure, neuro AIDS HIV pathogenesis, and HIV vaccines. SEARCH also has strong ties to the University of California, San Francisco in adult/pediatric neuro AIDS studies. Since its inception in 2005, SEARCH has conducted 18 studies, 5 of which were funded by the US NIH (4 R01s and 1 R21). In collaboration with investigators at the USMHRP, NIAID (Drs. Daniel Douek, Irini Sereti, Frank Maldarelli), Vaccine and Gene Therapy (VGTI), SEARCH is undertaking several lines of investigations to achieve HIV cure.
Please visit HIV-NAT and SEARCH websites for information on our work.